Nutritional Management in Patients Under Warfarin Therapy: A Comprehensive Review

Warfarin is an anticoagulant drug routinely used in the treatment and prophylaxis of patients with atrial fibrillation, venous thromboembolism (deep venous thromboembolism, pulmonary embolism), and mechanical heart valves. Due to its narrow therapeutic index and its property of inhibiting vitamin K-dependent clotting factors, its pharmacological activity requires close monitoring. In the management of patients on warfarin who are followed with INR monitoring, dietary vitamin K affects INR values, which poses a risk for thromboembolic complications or bleeding. Therefore, appropriate nutritional management in patients on warfarin is vital to achieve treatment goals and ensure patient safety. This review article aims to help healthcare professionals more effectively manage the nutritional status of patients on warfarin by comprehensively evaluating recommendations for nutritional management in patients on warfarin.

Keywords: Warfarin; Nutrition; Vitamin K; Thromboembolism; Bleeding; Patient education