Therapeutic Potential of Chamaejasmine: An Important Anticancer Metabolite of Stellera Chamaejasme L.

Human illnesses and secondary complications have long been treated with phytomedicine. The majority of herbal drugs were composed of numerous elements of medicinal plants that had therapeutic benefit for human health conditions. Stellera chamaejasme L., contains chamaejasmine as an important phytochemical. Chamaejasmine has potent pain-relieving potential and exerted antitumor activity. Scientific data about chamaejasmine pharmacological properties and therapeutic applications have been collected from a variety of scientific research databases. Additionally, scientific information has been gathered and examined to determine the advantageous function of chamaejasmine. Further, chamaejasmine has also been analyzed for their anticancer potential against cancerous disorders. Present review scientific data described the therapeutic effectiveness of chamaejasmine against cancers. Chamaejasmine scientific data also signified its biological potential in terms of its anti-cancer activity against osteosarcoma, breast cancer, cervical cancer, lung adenocarcinoma, hepatocellular carcinoma, larynx carcinoma, atopic dermatitis and glioblastoma. Present review also described pharmacokinetic parameters of chamaejasmine with its effectiveness on multidrug resistance. The present scientific data pertaining to review studies could be used to investigate the health beneficial aspects of chamaejasmine for their anticancer activity in the future.

Keywords: Anti-cancer; Atopic dermatitis; Breast cancer; Cervical cancer, Chamaejasmine; Glioblastoma; Hepatocellular carcinoma; Larynx carcinoma; Lung adenocarcinoma; Osteosarcoma; Pharmacokinetic